NFL Week 13 features a a number of key divisional matchups. In an important AFC South battle, the Houston Texans look to pull within one game of the division lead when they meet the Indianapolis Colts. The Colts are favored by 3.5 points as both C.J. Stroud and Daniel Jones have been battling injury concerns. Both, however, carry no injury designation heading into the game.

A non-divisional matchup with heavy AFC playoff race implications will be played on Sunday afternoon when Josh Allen and the Buffalo Bills (-3) take on Aaron Rodgers, who missed last week's game, and the Pittsburgh Steelers. Buffalo has won four of the past five meetings, with the Bills pulling out a 31-17 win in the last meeting on Jan. 15, 2024. Sunday's largest spreads are Vikings vs. Seahawks (-11.5), Rams (-10.5)

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