Inter Miami CF forward Lionel Messi celebrates after scoring against Nashville SC at Chase Stadium on Nov. 8, 2025.

Inter Miami are on the brink of winning its biggest prize since Lionel Messi's arrival in the summer of 2023. However, standing in the way of MLS Cup glory are the Vancouver Whitecaps.

The 30th edition of MLS Cup — which will be played Saturday, Dec. 6 — features an intriguing matchup. Both teams feature star power, with Miami featuring Messi and his former FC Barcelona teammates Jordi Alba, Sergio Busquets and Luis Suarez, and Vancouver featuring German legend Thomas Müller as well as goal-scoring threat Brian White and U.S. World Cup hopeful Sebastian Berhalter.

Here's how USA TODAY Network soccer experts see the 2025 MLS Cup playing out:

MLS Cup 2025 predictions

  • Jim Reineking: Inter Miami over Vancouver Whitecaps

Really feel like this could be a fun game to watch with hopefully plenty of action and goals. Both teams come into this championship showdown on absolute heaters. Vancouver has a "team of destiny" feel to it, but Lionel Messi profoundly tilts the balance of power Miami's way.

  • Jacob Shames: Inter Miami over Vancouver Whitecaps

Miami is as hot as it's been all season, having won each of its last three games by four goals heading into the final. Thomas Muller and the Whitecaps attack can keep pace, but Lionel Messi will be too much to deal with as Miami wins, 3-2.

  • Seth Vertelney: Inter Miami over Vancouver Whitecaps

The Herons have found the formula for victory lately, with Luis Suarez moving to the bench to provide Lionel Messi with younger, more dynamic attacking partners. That has led to three straight wins by a combined score of 13-1. It's hard to see anybody stopping them in this kind of form.

  • James Weber: Inter Miami over Vancouver Whitecaps

I don’t think even a team as good as the Whitecaps can slow down Lionel Messi, especially at home. Putting Mateo Silvetti in the lineup really made Miami unstoppable down the stretch.

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This article originally appeared on USA TODAY: MLS Cup predictions: Lionel Messi, Inter Miami heavy favorites to win

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