Oct 18, 2025; Nashville, Tennessee, USA; Inter Miami forward Lionel Messi (10) and defender Ian Fray (17) celebrate the goal of midfielder Telasco Segovia (8) against Nashville SC during the second half at Geodis Park.

Inter Miami and the Vancouver Whitecaps square off on Saturday for a star-studded MLS Cup 2025.

The Herons are looking to cap off what has been a truly dominant run in these playoffs.

With Lionel Messi at the peak of his powers and the supporting cast around him stepping up, Miami has steamrolled the competition to get within one win from glory.

This will be the final game in the illustrious careers of Sergio Busquets and Jordi Alba. Messi will want nothing more than to send his longtime teammates out with a trophy.

Watch Inter Miami vs. Vancouver Whitecaps on Apple TV

Vancouver will be hoping to go down to Florida and spoil the party. The Thomas Müller-led side has been through the postseason ringer, narrowly avoiding elimination several times.

The Whitecaps' resilience and spirit have gotten them this far. If they can muster up one more magical performance, their first-ever MLS Cup could be coming back to the Pacific Northwest.

If you are looking for betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of OddsWire.

Inter Miami vs. Vancouver Whitecaps game odds

Inter Miami vs. Vancouver Whitecaps prediction, pick

Vancouver has had a storybook season. However, Lionel Messi is inevitable. With two of his best friends playing in their last professional match, the greatest soccer player we've ever seen will put Miami on his back one more time.

Prediction: Inter Miami 3, Vancouver Whitecaps 1

Inter Miami vs. Vancouver Whitecaps channel, start time, streaming

  • When: Saturday, December 6
  • Where: Chase Stadium (Fort Lauderdale, FL)
  • Time: 2:30 p.m. ET
  • Channel/streaming: Fox, MLS Season Pass on Apple TV (Watch LIVE), Fox Deportes

This article originally appeared on Pro Soccer Wire: Inter Miami vs. Vancouver: MLS Cup betting odds, prediction, pick

Reporting by Rob Usry, Pro Soccer Wire / Pro Soccer Wire

USA TODAY Network via Reuters Connect