Stephanie Ruhle reached the end of her tether with Mike Johnson after his bizarre comments about the state of women’s brains.

“Holy Mary, Mother of God, pray for us sinners now and at the hour of our death. Amen. Are you kidding me? I mean, are you kidding me? Are you kidding me?!" she ground out on MS NOW’s The 11th Hour Friday night.

Ruhle’s astonishment came in response to the house speaker’s appearance on Katie Miller’s podcast late last month, during which he and his wife Kelly spoke about men and women’s differing mental capabilities.

“Men and women are different in this way, is that men can compartmentalize things,” Johnson said, with Kelly likening men’s brains to “waffles.”

“They have little compartments, and they can think on one little compartment at a time and close it,” th

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