Ballon d’Or winner Ousmane Dembélé and goalkeeper Lucas Chevalier will both miss Paris Saint-Germain's trip to Athletic Bilbao in the Champions League on Wednesday.
PSG said Dembélé is sick while Chevalier is still recovering from a right ankle injury.
It's another setback for Dembélé, who returned from a left calf injury against Tottenham at the end of November and only made two more appearances in the French league.
Before that, Dembélé had been sidelined several weeks by a right hamstring injury sustained while playing for France in September.
PSG will also still be without Morocco right back Achraf Hakimi, who has a sprained left ankle and faces a race against time to recover before the Africa Cup of Nations in his home country from Dec. 21.
Matvei Safonov is expected to start

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