Eli Lilly and Company announced Tuesday it will invest more than $6 billion to build a major new pharmaceutical manufacturing facility in Alabama, a blockbuster economic development win that state leaders say will be the largest initial investment in Alabama history.

The project, planned for the Greenbrier South area in Huntsville, will be a next-generation active pharmaceutical ingredient site focused on domestic production of “small molecule synthetic and peptide medicines,” according to the company.

Lilly says the facility is expected to create about 3,450 total jobs, including 3,000 construction jobs and 450 permanent, high-skilled roles such as engineers, scientists, operations personnel and lab technicians.

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