From Jerry Seinfeld and George Costanza to The Office ’s Michael Scott and Dwight Schrute, a really great sitcom duo is a thing of beauty. A great individual performance in a sitcom can be endlessly fun to watch, but the real meat and potatoes of a sitcom is how those actors (and their characters) interact with everyone else in the ensemble. Sitcoms are the perfect vehicle for a comic double act.

If you pair up Tina Fey and Alec Baldwin, or Catherine O’Hara and Eugene Levy, or Andre Braugher and Andy Samberg, then you can spin endless comedy gold. If you have Susie Essman yell at Larry David , or have Ty Burrell desperately clamoring for Ed O’Neill’s approval, the laughs will come naturally. These are the best-matched, best-written, best-acted sitcom duos in the history of the genre

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