All eyes will be on the AFC East this weekend when the 9-4 Buffalo Bills look to snap the 11-2 New England Patriots ' 10-game winning streak and get within one game of the division leaders with three weeks to go. After a rocky 1-2 start, the Pats have taken care of business, including beating the Bills in Buffalo back in Week 5. Buffalo is 5-3 since then and needs a win this week to have any shot at winning its sixth straight AFC East title.

Kickoff from Gillette Stadium is set for 1 p.m. ET on CBS and Paramount+ . The Bills are 2.5-point favorites, per the latest Bills vs. Patriots odds from DraftKings , while the over/under for total points scored is 49.5. Before making any Patriots vs. Bills picks of your own, make sure to look at the top NFL picks from the SportsLine Pr

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