The Pittsburgh Pirates (22-38) and the Houston Astros (32-27) begin their three-game series on Tuesday. The Astros head into this game winning two of their last three games. In Sunday's tilt, Houston shut out the Tampa Bay Rays 1-0. As for the Pirates, the San Diego Padres outlasted them 6-4 on June 1. Lance McCullers Jr. (0-1, 5.89 ERA) will start for Houston. Paul Skenes (4.5, 2.15 ERA) is on the hill for the Pirates.

First pitch from PNC Park is set for 6:40 p.m. ET. Pittsburgh is a -159 favorite on the money line (risk $159 to win $100) in the latest Astros vs. Pirates odds from FanDuel Sportsbook, while the over/under for total runs scored is 7. Before making any Astros vs. Pirates picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model

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