The 2025 FedEx St. Jude Championship at TPC Southwind marks the first leg of the FedExCup Playoffs. Scottie Scheffler looks to become the first golfer to win back-to-back FedExCup titles, while Hideki Matsuyama hopes to become the first golfer to repeat at TPC Southwind since Daniel Berger (2016-17). Scheffler is the +280 betting favorite, according to the latest 2025 FedEx St. Jude Championship odds, while Matsuyama is a +4500 longshot. The 2025 FedEx St. Jude Championship first-round tee times begin on Thursday at 8:20 a.m. ET.

Longshots on betting sites have fared well at the FedEx St. Jude Championship in recent years, with Lucas Glover (2023), Will Zalatoris (2022) and Tony Finau (2021) all finishing on top of the leaderboard. Viktor Hovland, who finished T-2 at the FedEx St. J

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