Duke, Stanford and Northwestern all made deep cuts recently.

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Six months into his second term, President Donald Trump has forced changes at many of the nation’s wealthiest universities, some of which have shed hundreds of jobs amid federal funding issues and investigations.

While sector layoffs are so frequent that Inside Higher Ed has dedicated monthly coverage to rounding up such reductions, those actions are more common at small, cash-strapped colleges or state institutions reeling from budget cuts. But universities with multibillion-dollar endowments have been among those making the deepest cuts in the first half of 2025, often driven by freezes on fede

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