TOPLINE:

Sequential treatment with cryotherapy followed by 1% tirbanibulin was well tolerated, improved lesion clearance, and prevented new lesions in solid organ transplant recipients (SOTRs) with actinic keratosis (AK) compared with cryotherapy alone, a study found.

METHODOLOGY:

Researchers evaluated 37 SOTRs (mean age, 70.7 years; 35 men), between May and December 2024. Each participant were at least 1 year post-transplant, had four to eight AKs on two 25 cm² areas of the face and/or scalp.

Participants underwent baseline cryotherapy on both target areas; one area then received a 5-day course of 1% tirbanibulin ointment 1 month later, and the other area received no further treatment.

The primary outcome was the variation in the AK count within the sequential treatment area at 4 m

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