Emergency services are responding to a collision at Carlisle's Bus Station on Lonsdale Street.
The incident was reported to police at 8:26am this morning.
Forensic Collision Investigation Units are on the scene alongside paramedics.
A spokesperson for Cumbria Police said: "There is currently a full closure on Lonsdale Street. "Motorists and pedestrians are asked to avoid the area."
No bus services are able to leave the station due to the cordon placed by emergency services.
On social media, Stagecoach said: "Due to an incident, Carlisle Bus Station is closed for the foreseeable, any passengers wishing to get a bus going West should get the bus at the Apple Tree on Lowther Street or at West Tower Street.
"The 104 and 685 services will use the top of Warwick Road outside the Halsto