Key Takeaways
A higher adherence to the MIND diet was tied with lower odds of hippocampal sclerosis in an autopsy study.
Mediation analyses showed that the MIND diet was associated with less dementia at the time of death.
This study may be the first to report that the link between diet and dementia is partly mediated by hippocampal sclerosis.
Adherence to the MIND diet -- a hybrid of the Mediterranean diet and the Dietary Approaches to Stop Hypertension (DASH) diet -- was tied to a lower likelihood of hippocampal sclerosis and related pathologies, autopsy data showed.
Among 809 autopsied participants, higher MIND diet scores were linked with lower odds of hippocampal sclerosis (OR 0.78, 95% CI 0.65-0.95) after controlling for age at death, sex, education, total calories, APOE4 statu