Health has historically been the only thing that could hold Giancarlo Stanton back from producing massive power numbers, and he's proven in 2025 that he's still a threat to go yard whenever he's in the lineup. Stanton has 10 home runs in 39 games this season and enters a pivotal AL matchup on Sunday sitting on 439 home runs for his career. He has an .898 OPS against right-handed pitching this season, and the Astros will send righty Jason Alexander to the bump for the 1:35 p.m. ET first pitch.
Alexander sports a 5.97 ERA on the season, and that's a big reason why Stanton (+350 in the MLB home run odds) is one of our top MLB HR picks on Sunday. MLB home run props are available for almost every player in every game at various sportsbooks , and SportsLine's proven computer model ca