A Massachusetts-based company that creates specialized packaging for life science uses plans to move all of its manufacturing operations out of the state this fall and lay off the employees currently doing that work.

Franklin-based Cold Chain Technologies will lay off 82 people between Oct. 1 and the end of the year, according to a Massachusetts Workers Adjustment Retraining Notice filed with the state on Aug. 8. Manufacturing will be moved from the company’s headquarters at 135 Constitution Blvd. in Franklin to its other U.S. sites in Pennsylvania, Tennessee and Texas, according to a letter from the company to the state Department of Career Services.

Cold Chain Technologies did not respond to a request for comment.

Other employees will remain at the Franklin site for “certain operati

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