Residents in Pittsburgh’s West End can expect mosquito spraying Wednesday evening after recent samples tested positive for West Nile virus, the Allegheny County Health Department announced.

From 8 to 11 p.m., the city’s Chartiers, Crafton Heights, Elliott and Sheraden neighborhoods, along with the boroughs of Crafton and Ingram, will be sprayed with Zenivex E20, a pesticide that is not harmful to humans or pets, according to the health department.

The upcoming treatment is the latest in the county’s efforts to lower the local mosquito population and “minimize the risk of human transmission,” the department said. In the event of rain, the spraying will take place Thursday during the same hours.

West Nile virus is the leading mosquito-borne disease in the U.S. In the past several weeks,

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