TOPLINE:
Exposure to monoethyl phthalate (MEP) — a chemical commonly found in industrial and personal care products — was associated with a substantially elevated risk for subclinical coronary atherosclerosis among men working in a car assembly unit.
METHODOLOGY:
Researchers conducted a cross-sectional study to assess whether urinary phthalates showed any association with subclinical coronary atherosclerosis.
They included 1119 Spanish male workers (mean age, 50.9 years) from a car assembly plant.
A total of 11 urinary phthalate metabolites were measured using liquid chromatography coupled to tandem mass spectrometry.
Participants underwent CT scans between January 2011 and December 2014 to determine coronary artery calcium ; subclinical coronary atherosclerosis was defined as a