Mouse pancreatic islet visualised using immunofluorescent microscopy. — Colours: red = insulin antibody, blue = DAPI = nuclei, green unspecific anti-mouse secondary antibody (stains mostly intercellular matrix) Dimension: real width 326µm Generated in the Solimena lab, Paul Langerhans Institute Dresden Jakob Suckale from Wikimedia Commons
For decades, the ambitious goal of regenerative medicine has been to replace damaged or lost tissues with healthy, functioning ones. Nowhere is this objective more compelling—or challenging—than in type 1 diabetes. Countless research efforts over the years have sought to restore these cells. Breakthroughs in cell engineering and transplantation are beginning to overcome long-standing roadblocks, and these r ecent advances are a significant achievem