Key Takeaways

"Clear" e-cigarettes had disproportionately greater cardiovascular effects than other types of vapes when smoking conditions were controlled.

"Clear" e-cigarettes contained synthetic coolants, menthol, and other flavorings despite their marketing.

Acute increases in blood pressure may be related to the synthetic coolants reducing tobacco or nicotine harshness and facilitating deeper inhalation.

E-cigarettes marketed as "clear" may get around flavor bans, but they appear to have a greater health impact than other types of vapes, according to findings from an observational cohort study.

Among participants in the Cardiovascular Injury due to Tobacco Products 2.0 study, smokers of "clear" e-cigarettes had modestly but significantly greater increases in blood pressure, heart

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