Key Takeaways

Women with obesity have lower rates of IVF success, increased risks of miscarriage, and lower birth rates.

This study suggests that weight loss before pursuing IVF may improve pregnancy rates for women with obesity.

However, the effect on pregnancies resulting from IVF was uncertain.

Losing weight prior to pursuing in vitro fertilization (IVF) may increase pregnancy rates among women with obesity, though it did not appear to improve IVF outcomes, according to a systematic review and meta-analysis.

Among 12 randomized controlled trials, there was moderate certainty that pre-IVF weight loss interventions were linked to an increase in total pregnancy rates (risk ratio [RR] 1.21, 95% CI 1.02-1.44; 11 studies) and pregnancies resulting from unassisted conception (RR 1.47, 95%

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