While the AFC North and AFC West each sent at least two teams to the playoffs last year, no one outside of Houston in the AFC South and Buffalo in the AFC East contended for the postseason.

The AFC South boasted multiple playoff teams in both 2019 (Houston, Tennessee) and 2020 (Indianapolis, Tennessee), but only one team from this division has made the playoffs in each of the last four years.

And based on the 2025 NFL preseason win total odds, the AFC South once again looks light on postseason contenders after Houston.

Check out Newsweek Sports Betting later this week for our outlook on the AFC East and the rest of the conference, and also click below for a look at all 16 teams in the NFC.

2025 AFC South Win Total Odds

With 2023 NFL AP Offensive Rookie of the Year CJ Stroud back

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