SEATTLE — With increasing survival rates after allogeneic hematopoietic stem cell transplantation (HSCT) in children, dermatologists may be seeing more skin conditions associated with HSCT, including the cutaneous manifestations of graft-vs-host disease (GVHD), according to Jennifer T. Huang, MD, associate professor of dermatology and pediatrics, Harvard Medical School, Boston.

GVHD is the most common complication following HSCT, and while it can affect any body organ, the skin is the most commonly involved. “In the US, there are 85 centers in 37 states that perform pediatric allogeneic transplants,” Huang said at the Society for Pediatric Dermatology (SPD) 2025 Annual Meeting . In the US, about 1400 allogeneic transplants are performed each year, and 15% are in children, she noted.

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