TOPLINE:

A new risk stratification tool known as CA4TCH — which relies solely on clinical history — could help predict which patients with a suspected hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) will have a hypersensitivity confirmed during a drug provocation test.

METHODOLOGY:

To develop and validate CA4TCH, researchers conducted a retrospective study of 1035 patients who presented with suspected NSAID hypersensitivity at the allergy unit of the University Hospital of Montpellier in Montpellier, France, between February 2001 and December 2020 and underwent drug provocation testing.

Using elements of the clinical history — including sex; age at the last reaction; reaction onset ≤ 24 hours; whether the last reaction occurred in the past 5 years; history of anaphyla

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