For decades, creatine has been the go-to supplement for gym enthusiasts seeking bigger lifts and stronger muscles. Long dismissed by some as a “gym bro” staple, it’s now attracting the attention of scientists and health experts for a completely different reason: its potential to boost brain performance.

From Muscle Fuel to Mental Edge

On a recent episode of the Diary of a CEO with Steven Bartlett, Dr. Rhonda Patrick, a biochemist known for her work on nutrition and aging, admits she once saw creatine purely as a muscle-building aid. That changed when research began revealing its neurological benefits. While our bodies naturally produce 1–3 grams daily—mainly in the liver and brain—most of it is quickly consumed by energy-hungry muscles.

In resistance training, creatine helps regenerate

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