Key Takeaways

Genetic susceptibility accounts for 20% of ovarian cancer risk, and risk-reducing bilateral salpingectomy remains the gold standard for prevention.

In this study, about 24% of patients with high-grade serous ovarian cancer had missed opportunities for risk-reducing surgery before cancer diagnosis.

Among the women with a first-degree family history of ovarian cancer, 43.2% had mutations that increased susceptibility to ovarian cancer.

Almost a fourth of women with high-grade serous ovarian cancer (HGSOC) had opportunities for risk-reducing surgery a year or more prior to diagnosis, a large retrospective study suggested.

Data showed that 445 of 1,877 (23.7%) patients had "missed opportunities" for salpingectomy when they underwent surgery for permanent contraception or abd

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