TOPLINE:

In patients with diabetes, using metformin for at least 5 consecutive years was associated with a lower risk of developing age-related macular degeneration (AMD), particularly the dry type of the condition.

METHODOLOGY:

Researchers conducted a retrospective cohort study using data from a federated health research network to examine the association between the use of metformin and the risk of developing AMD in patients with diabetes.

They included 7496 patients aged 60 years or older with diabetes who attended two or more eye care visits at least 1 year apart; none had a diagnosis of AMD at or prior to every visit.

Those who used metformin at least once per year for 5 or more consecutive years before their eye care visit (n = 3748) were compared with matched patients (n = 37

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