Q&A: Guidance updated for acute pulmonary histoplasmosis updated

Key takeaways:

Guidelines for the management of pulmonary histoplasmosis were last published in 2007.

The new guidelines use language to reflect the uncertainty associated with available data.

The Infectious Diseases Society of America has begun updating its clinical practice guidelines for managing histoplasmosis for the first time in 18 years.

In the first two updates, the IDSA published recommendations focused on the treatment of asymptomatic Histoplasma pulmonary nodules and mild or moderate acute pulmonary histoplasmosis in adults, children and pregnant people.

The guidelines suggest against the routine treatment of adults and children with asymptomatic Histoplasma pulmonary nodules, unless they have an elevated risk for severe histoplasmosis, in which case treatment or incre