TOPLINE:

High baseline parathyroid hormone levels were associated with single-gland disease and successful localization of the affected gland on preoperative imaging, aiding surgical planning for hyperparathyroidism. Additionally, a decline in intraoperative parathyroid hormone levels of < 70% and postoperative serum calcium levels > 10 mg/dL at 6 months predicted the risk for recalcitrant disease despite parathyroidectomy.

METHODOLOGY:

Monitoring biochemical profiles in patients undergoing surgery for hyperparathyroidism enables surgeons to predict single-gland vs multigland primary hyperparathyroidism and monitor patients at a higher risk for recalcitrant disease.

Researchers conducted a retrospective cohort study to assess the associations of preoperative imaging localization, intra

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