A rundown of college football’s toughest schedules in 2025 could just list every team in the SEC , and to a slightly lesser extent the Big Ten .

That’s life in these two heavyweight conferences, where adding teams such as Texas and Oklahoma in the SEC and Southern California, Oregon and more to the Big Ten has cranked up the level of regular-season difficulty.

USA TODAY Sports has a preseason glance at the Bowl Subdivision’s most difficult slates includes plenty of teams from the SEC and Big Ten, including Wisconsin, Florida , Arkansas and Ohio State.

But there are multiple teams in the ACC staring down a rocky road from September to December. One, Stanford, will face off with Notre Dame and other difficult games under interim coach Frank Reich.

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