Adults with wheezing mainly caused by chronic pulmonary conditions showed significantly accelerated epigenetic aging than those without wheezing, based on data from more than 2000 individuals.
Increasing evidence indicates that aging contributes to the risk for chronic respiratory diseases, but the impact of epigenetic changes stemming from DNA methylation has not been well studied, wrote Javier Perez-Garcia, MD, of Stanford University, Stanford, California, and colleagues.
In a study published in the European Respiratory Journal, the researchers used data from the National Health and Nutrition Examination Survey (NHANES) to analyze the association between epigenetic age acceleration in whole-blood and chronic respiratory diseases.
The study population included 2346 adults aged 50 yea