Anderson's fantasy football RB3s to target in deep leagues. Third-string running backs with contingent upside include Keaton Mitchell and more.

Every season, fantasy football managers' hearts are broken by injuries to starting running backs — and backup running backs, too.

Savvy fantasy managers will keep tabs on third-string running backs so they can add them via the waiver wire or the final rounds of drafts.

Here are eight running backs worthy of a look in deep fantasy football leagues. Be sure to check all of our fantasy football rankings for 2025:

2025 fantasy football rankings

Running back (RB) fantasy football rankings

Wide receiver (WR) fantasy football rankings

Tight end (TE) fantasy football rankings

Quarterback (QB) fantasy football rankings

Defense (D/ST) fantasy foo

See Full Page