HOLLY SPRINGS, N.C. — A hallway as long as three football fields connects four buildings at Fujifilm Biotechnologies' new biologics manufacturing plant in Holly Springs, North Carolina.

The first two buildings are preparing to open this fall to produce drug substance, essentially the base of biologic drugs, for Fujifilm's initial customers Regeneron and Johnson & Johnson . The second two facilities are still under construction, with plans to open in 2028.

Fujifilm's timing couldn't be better, as President Donald Trump threatens to impose tariffs on pharmaceuticals to encourage companies to make more medicines in the U.S. But the plans for this complex were underway well before Trump proposed higher duties.

It's taken five years and more than $3 billion to turn the

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