The San Francisco 49ers went 6-11 and missed the playoffs last season but are +160 at ESPN BET to win the NFC West in 2025.

Right there with them are the Los Angeles Rams (+175), who last season advanced to the divisional round of the playoffs. At 20-1, the 49ers and Rams are among the top 10 teams with the best odds to win Super Bowl LX.

But it's not a two-team race, as the division race projects to be one of the most competitive in the NFL. The Arizona Cardinals and Seattle Seahawks both have their win totals posted at 8.5. San Francisco is at 10.5, and the Rams are at 9.5.

How will things play out this season? Here are the season-long odds for the NFC West teams and our favorite bets.

Division betting previews: br/> AFC East | AFC North | AFC South | AFC West br/>

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