(CNN) — Multiple fatalities and injuries, including children, were reported Friday after a tour bus with about 50 passengers headed back to New York City from Niagara Falls crashed into a ditch, state police said.

The bus rolled over after losing control for “unknown reasons,” New York State Police spokesperson James O’Callaghan said at a news conference.

Several people were entrapped and others were ejected from the bus, O’Callaghan said. Authorities are actively responding to the crash scene and “a lot” of rescues are still ongoing, noting some people who are entrapped may still be alive.

“We believe there is a child that is a fatality,” he said.

Translators are also coming to assist police as most of the people on the tour bus were Indian, Chinese and Filipino, O’Callaghan said.

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