ST. LOUIS — Dr. Stuart Kornfeld, a groundbreaking medical researcher and longtime professor of medicine at Washington University, died Sunday in St. Louis from complications of Parkinson's disease. He was 88.

Kornfeld was a pioneer in the study of glycoproteins, molecules made up of sugars attached to proteins. His work spurred various clinical innovations, including treatments for some inherited genetic disorders such as Tay-Sachs and Gaucher diseases.

Dr. Victoria Fraser, chair of WashU's Department of Medicine, said Kornfeld's basic research has had "outsized influence" in many fields, including metabolism, cell biology, biochemistry, genetics, microbiology, immunology, hematology and oncology.

The university said Kornfeld and his wife, fellow researcher Rosalind Hauk Kornfeld, who d

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