TOPLINE:
Clinical assessment combined with musculoskeletal ultrasound examination revealed distinct phenotypes in difficult-to-treat psoriatic arthritis (PsA), with a greater inflammatory burden and more aggressive disease being observed in those with persistent inflammatory PsA than in those with non-inflammatory PsA.
METHODOLOGY:
Researchers conducted a cross-sectional study between March and December 2024 at two Italian centres to differentiate patients with persistent inflammatory from non-inflammatory PsA using clinical examinations and ultrasound in a cohort of patients with difficult-to-treat PsA.
They included 517 adults diagnosed with PsA who received treatment with biologic and/or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs), with difficult-to-treat