Venus Williams battled bravely before bowing out of the US Open on her return to Grand Slam tennis on Monday as Melbourne champion Madison Keys suffered a shock first-round exit.

The second full day of action in New York saw all eyes turn to the Arthur Ashe Stadium's night session, where the 45-year-old Williams lost in three sets to 11th seed Karolina Muchova.

Williams only returned to competitive tennis in July following a 16-month absence from the sport and had been granted a wild card into the main draw at Flushing Meadows.

But hopes of a fairytale run -- 28 years after her debut in the tournament in 1997 -- ended in a 6-3, 2-6, 6-1 loss to Muchova, who was not even born when Williams turned professional in 1994.

"I didn't win today but I'm very proud of the way I played," Williams

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