(Reuters) -The U.S. Open second round kicks off on Wednesday, with Novak Djokovic pursuing his quest for a record 25th Grand Slam title, while women’s top seed Aryna Sabalenka continues her title defence and home favourite Ben Shelton faces veteran Pablo Carreno Busta.

TOP MEN’S MATCH: NOVAK DJOKOVIC V ZACHARY SVAJDA

A 25th major title has eluded Novak Djokovic at the last seven slams. If the 38-year-old fails to win the U.S. Open, he will complete two calendar years without a Grand Slam title for the first time since 2010.

On paper, the Serbian got off to a decent start, beating Learner Tien in straight sets. But the 19-year-old forced a tiebreaker in the second set as Djokovic struggled with a right foot blister.

“Yeah, it’s slightly a concern. I don’t know. I don’t have any injury o

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