The Week 1 college football schedule brings dozens of intriguing matchups that will shape the early College Football Playoff picture. Games run from Thursday through Monday, highlighted by three ranked matchups involving top-10 teams with Texas vs. Ohio State (-1.5), LSU vs. Clemson (-3.5) and Notre Dame vs. Miami (+2.5). Those college football spreads are all within a touchdown, but there are also some giants numbers on the Week 1 college football odds board as some teams are starting out with easier opponents.

The No. 2 Penn State Nittany Lions are 44.5-point favorites over Nevada, while the fifth-ranked Georgia Bulldogs are favored by 39.5 points over Marshall. Making college football predictions for season openers are always a bit difficult given the amount of player movement there is

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