Ismael “El Mayo” Zambada , the co-founder of the Sinaloa cartel , is set to face the rest of his life behind bars as the Trump administration ramps up its efforts to dismantle cartels.

Zambada, 75, confessed in a Brooklyn, New York, courtroom Monday that he had coordinated with Mexican officials to smuggle drugs into the US for decades — and ultimately pleaded guilty to serving as principal leader of a continuing criminal enterprise and racketeering conspiracy.

The Trump administration has pledged to take down the cartels — and experts predict Zambada’s guilty plea paves the way for the Justice Department to launch more indictments against high-profile cartel members moving forward and exerts additional pressure on Mexico to comply with US requests.

“It gives Trump powerful politica

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