Tulane 24, Northwestern 17
Predicting openers in the transfer portal era is twice as hard as in the old days, with almost every team undergoing dramatic roster turnover. This much we know, though: The Wildcats traditionally struggles on offense, and the Green Wave is loaded with defensive talent. Points could be at a premium since quarterback Jake Retzlaff is starting a month after transferring to Tulane and has no proven receiver, but Retzlaff came through in the clutch several times at BYU last season and likely will do it again.