No. 21 Iowa State football makes its Jack Trice Stadium season debut against South Dakota at 2:30 p.m. CT Saturday, Aug. 30. FOX will televise the contest.

The Cyclones kicked off the college football season with a Week 0 win, 24-21, over rival Kansas State in Dublin, Ireland. South Dakota, meanwhile, is making its season debut.

Here's some predictions of how several experts believe the Iowa State -South Dakota matchup will go. Stream Iowa State vs. South Dakota free with Fubo

Iowa State vs. South Dakota odds, money line, over/under

Odds courtesy of BetMGM as of Friday, Aug. 29. Expert MLB daily picks: Unique MLB betting insights only at USA TODAY

Spread : Iowa State -14.5

Moneyline: Iowa State -670, South Dakota +485

Over/under : 46.5

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