Ranked opponents square off to kick off the 2025 college football season when the sixth-ranked Notre Dame Fighting Irish clash with the 10th-ranked Miami (Fla.) Hurricanes on Sunday night. Both teams enter the game having had to replace their starting quarterbacks from a year ago. The Fighting Irish (14-2 in 2024), who lost to Ohio State 34-23 in the national championship game, were 3-0 on the road last year. The Hurricanes (10-3 in 2024), who placed third in the ACC at 6-2, were 6-0 on their home field a season ago.

Kickoff from Hard Rock Stadium in Miami Gardens, Fla., is set for 7:30 p.m. ET. Notre Dame leads the all-time series 19-8. The Fighting Irish are 2.5-point favorites in the latest Notre Dame vs. Miami odds from SportsLine consensus, while the over/under for total points s

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