As President Donald Trump continues to implement significant personnel changes and investigations, attorney Abbe Lowell is emerging as a key figure in the legal battles that follow. The 73-year-old white-collar defense attorney has represented a range of high-profile clients from both political parties, including members of Trump's family and administration, as well as those perceived as his adversaries.

Lowell has been vocal about his long-standing commitment to challenging what he sees as government overreach. "I have basically challenged the overreach of federal agencies in every administration since Ronald Reagan's. It didn't matter whether it was a Democratic or Republican administration. If the government overreaches, then [the] lawyer's job is to put the government in the right place," he stated on MSNBC.

Recently, Lowell has focused on contesting Trump's recent firings, including that of Lisa Cook, a Federal Reserve Governor, and Susan Monarez, the recently appointed CDC director. Cook's legal team, which includes Lowell, filed a lawsuit against Trump's decision to fire her, labeling it "unprecedented and illegal." During a hearing regarding Cook's case, Lowell argued that "allegations of fraud have become the weapon of choice," suggesting that Trump aims to gain control of the Federal Reserve to influence interest rates.

In a statement regarding Monarez's dismissal, Lowell and other attorneys claimed she was "targeted" for refusing to endorse what they described as "unscientific, reckless directives" and for not dismissing dedicated health experts.

Lowell is also reportedly in discussions with John Bolton, Trump's former national security adviser, who has been a frequent target of Trump's ire. This comes after the FBI conducted a search of Bolton's home and office, an action Trump claimed he was unaware of.

After Trump began his second term, Lowell established his own law firm, Lowell & Associates, to represent individuals he believes have been "unlawfully and inappropriately targeted" by the Trump administration. He criticized the administration's actions, stating, "What President Trump and the people who carry out his mandate – it makes George Orwell's '1984' look like a mother goose nursery rhyme. I mean, it is just beyond comprehension."

Lowell's firm has taken on various clients affected by the Trump administration, including New York Attorney General Letitia James. James faced a civil suit against Trump that initially resulted in a $454 million fraud penalty, which was later overturned by an appeals court. In April, she was referred to the Department of Justice over mortgage fraud allegations, which she has denied.

Additionally, Lowell represents Miles Taylor, a former Trump administration official who has publicly criticized Trump. The president labeled Taylor a "traitor" and ordered an investigation into him, accusing him of treason, which Taylor has denied. Lowell is also defending Mark Zaid, the attorney for the whistleblower whose security clearance Trump revoked in March. In a complaint, Lowell described this action as "a dangerous, unconstitutional retaliation by the President of the United States against his perceived political enemies."

Despite his recent focus on opposing the Trump administration, Lowell has a history of representing clients from both sides of the political spectrum. He notably represented Hunter Biden, who faced federal gun-related charges and later pled guilty to tax charges before receiving a pardon from his father, President Joe Biden. Conversely, he also defended Jared Kushner and Ivanka Trump during the investigation into Russian interference in the 2016 election.

Lowell's legal expertise has been recognized in various high-profile cases, including the acquittal of Tom Barrack, a Trump ally, and his aide Matthew Grimes, who were accused of foreign lobbying. Lowell has also served as Chief Minority Counsel during the impeachment proceedings of former President Bill Clinton and defended Democratic Senator Bob Menendez in a federal bribery case.

A graduate of Columbia Law School, Lowell has held several significant positions, including roles in the Justice Department during the Carter administration and as Special Counsel to the House Ethics Committee.