A teenager is fighting for her life and a man is in hospital after a suspected shooting followed by a car crash in Melbourne overnight.

Emergency services were called to the scene after a car and a truck collided near the Hume Freeway ramp and Cooper Street in Epping at about 9.30pm.

One of the occupants of the car, a 23-year-old man, was found to have serious injuries consistent with gunshot wounds.

Another person in the car, an 18-year-old woman, suffered life-threatening injuries in the crash.

Both of them were taken to hospital.

The driver of the truck was not injured and remained on the scene.

Police do not believe the truck driver was involved in the 23-year-old man's shooting.

 Police found a car on fire a short distance away on Cooper Street and are investigating

See Full Page