‘General Hospital’ Cast These 30 Actors Before They Became Huge Stars | AJ Michalka, Amber Tamblyn, Annie Ilonzeh, Antonio Sabato Jr, Bridgit Mendler, Chrissie Fit, Darby Stanchfield, Demi Moore, EG,

General Hospital has been a major launching pad for Hollywood stars over the years!

The long-running soap, which first premiered on ABC back in 1963, just marked its incredible 62nd anniversary in April 2025.

While plenty of actors have stuck with their beloved roles for decades, the daytime drama has also been the starting point for tons of celebs who later made the leap to primetime TV and blockbuster films.

Stars like James Franco , Chandra Wilson , Elizabeth Taylor , and more have had guest arcs on General Hospital after they were already famous, so we’re not including them here.

Browse through the slideshow to see all of the actors who were on General Hospital before becoming famous…