Security, sovereignty, tariffs, trade, drugs and migration — all hot-button issues for the Trump administration and its neighbors in the Western Hemisphere — will top Secretary of State Marco Rubio's agenda this week on his third trip to Latin America since becoming chief U.S. diplomat.

The visit comes as the Trump administration has dramatically stepped up operations against drug cartels in the Caribbean, including recent military deployments and what it said was a lethal strike on a suspected drug-carrying vessel.

In talks with leaders in Mexico and Ecuador on Wednesday and Thursday, Rubio will make the case that broader, deeper cooperation with the U.S. on those issues is vitally important to improving health, safety and security in the Americas and the Caribbean.

Yet, President Dona

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