Gangland figure Tony Mokbel suffered a substantial miscarriage of justice because he was misled and deceived for years before pleading guilty to drug offences, his lawyers have argued.

Mokbel is fighting to quash drug-trafficking and importation convictions in the Victorian Court of Appeal, claiming they were tainted because of barrister-turned-informer Nicola Gobbo.

Gobbo was registered as a Victoria Police informer from 2005 to 2009 and was acting as Mokbel's lawyer for four years before he fled to Greece in 2006.

She continued to advise him when he was extradited to Melbourne in 2008.

Barrister Tim Game SC argued Gobbo not only "pretended" to be Mokbel's lawyer while informing, she encouraged two of her clients to make statements against him.

The statements from the two men,

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