The 2025 NFL Kickoff Game signals the return of professional football, and the defending world champions will be in action after hoisting their Super Bowl banners. The Philadelphia Eagles will host the Dallas Cowboys , and the Eagles are 8.5-point favorites, while the latest NFL odds list the over/under at 48.5 points. There are also dozens of NFL player props being offered, and alternate NFL props provide a chance to either enhance your payout or take a more risk-averse approach. For example, A.J. Brown's over/under for total receptions is 5.5, but if you think he'll be heavily involved in Philadelphia's passing attack, you can find him to catch 8+ passes at +403 (risk $100 to win $403).

Meanwhile, Saquon Barkley rushed for 167 yards in Week 17 against the Cowboys last year, an

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